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Résumé :
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Objective : Describe and compare the clinical profile of schizophrenic patients with and without obsessive-compulsive symptoms and obsessive-compulsive disorder (OCD) patients. Methods : A descriptive and analytical cross-sectional study was carried out at the psychiatry department of Hassan II University Hospital in Fez over 12 months to compare three groups of patients: “schizo-obsessive” (n = 32), “schizophrenia” (n = 34), and “OCD” (n = 46). All participants (n = 112) were assessed using the mini-international neuropsychiatric interview (MINI), the Yale-Brown obsessive-compulsive scale (Y-BOCS), the Brown assessment of beliefs scale (BABS), the Hamilton anxiety rating scale (HAM-A), the Beck's depression inventory (BDI-II), the positive and negative syndrome scale (PANSS), and the clinical global impressions–severity scale (CGI-S). Results : The “schizo-obsessive” group differed from the “schizophrenia” group in: more severe psychotic symptoms (mean = 64.16 ± 17.049, P < 0.001), higher anxiety (mean = 8.87 ± 5,655, P < 0.001) and depression (mean = 7.50 ± 5.989, P < 0.001) scores, more prevalent suicide attempts (46.9%), higher illness severity score (mean = 5.13 ± 1.157, P = 0.02), and more professional disinsertion (78.1%). The “schizo-obsessive” group (mean= 14.47 ± 3.388) had significantly poor insight (P < 0.001) compared to the “OCD” group (mean= 8.35 ± 4.542). There were similarities in the obsessive and compulsive themes between the “schizo-obsessive” and the “OCD” groups, with no significant difference of severity (P = 0.26). Conclusion : A careful assessment of obsessive symptomatology is essential in schizophrenia for better patient management and prognosis. [résumé d'auteur]
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![Clinical profile of schizophrenia comorbid with obsessive-compulsive symptoms: A comparative study [Le profil clinique de la schizophrénie en comorbidité avec les symptômes obsessionnels compulsifs : une étude comparative]](https://bibliotheques.ghu-paris.fr/img_cache/ghuparis_record_155138.webp)
